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Tsis txhob nco qhov hloov tshiab. Sau npe kom tau txais xov xwm Alliance tus kws kho mob.

Kev sau tshuaj opioids nrog rau cov tshuaj tiv thaiv kab mob: nkag siab txog qhov txaus ntshai 

Tus neeg muab kev pabcuam Icon

Ntau tshaj li ib nrab ntawm cov tshuaj opioid hauv Tebchaws Meskas tau sau los ntawm cov neeg mob uas muaj kev puas siab puas ntsws, nrog rau cov neeg mob uas siv tshuaj tiv thaiv kab mob. Piv nrog rau cov pej xeem, cov neeg mob uas muaj kev puas siab puas ntsws hnyav yog 2.5 npaug ntau dua yuav raug kho nrog opioids rau qhov mob ntev. Nws yog ib qho tseem ceeb uas cov kws kho mob yuav tsum ceev faj thaum muab tshuaj opioids rau cov neeg mob uas siv tshuaj tiv thaiv kab mob, xws li Kev siv cov chav kawm tshuaj no ua ke tuaj yeem ua rau qaug zog ntau dhau, ua pa nyuaj siab, overdose thiab tuag.

Kev cai lij choj 

Xyoo 2016, US Food and Drug Administration (FDA) tau tshaj tawm lub thawv dub ceeb toom txog kev sib xyaw tshuaj opioids thiab tshuaj tiv thaiv kev puas siab puas ntsws vim muaj kev pheej hmoo ntawm kev nyuaj siab ua pa. Xyoo 2018, Tebchaws Asmeskas Cov Neeg Sawv Cev tau dhau los ntawm Txoj Cai Pabcuam Rau Cov Neeg Mob thiab Zej Zog los txhawb kev siv tshuaj opioid tiv thaiv, rov zoo, thiab kho.

Antipsychotics nrog kev pheej hmoo siab ntawm kev noj tshuaj ntau dhau 

Thaum noj nrog opioids, sedating antipsychotics yog txuam nrog kev pheej hmoo siab (txog 60%) ntawm kev siv tshuaj ntau dhau piv rau cov tshuaj tiv thaiv tsis zoo. Kev hais lus dav dav, cov tshuaj tiv thaiv kev puas siab puas ntsws tuaj yeem raug faib ua sedating (xws li chlorpromazine, clozapine, olanzapine thiab quetiapine) thiab tsawg dua los yog tsis noj tshuaj (xws li, aripiprazole, haloperidol, lurasidone, risperidone thiab ziprasidone) raws li histamine-1 receptor affinity (Ki< los yog ≥20, ntsig txog). 

Txoj kev tiv thaiv cov neeg mob 

Thov xav txog cov kev ceev faj hauv qab no thaum muab tshuaj opioids rau cov neeg mob noj tshuaj tiv thaiv kab mob.  

  • Txwv tsis pub sau tshuaj kho mob opioid nrog sedating antipsychotics rau cov neeg mob uas lwm txoj kev kho mob tsis txaus. 
  • Yog tias tsim nyog siv tib lub sijhawm, txo qhov pib noj tshuaj opioid thiab titrate rau kev kho mob. Siv cov koob tshuaj qis tshaj plaws thiab siv sijhawm kho tsawg kawg nkaus. 
  • Saib xyuas cov neeg mob rau serotonin syndrome. Tso tseg tag nrho cov tshuaj serotonergic thiab pib kho cov tsos mob yog tias serotonin syndrome tshwm sim. Kev noj tshuaj opioids nrog lwm cov tshuaj uas cuam tshuam rau serotonergic neurotransmitter system tau ua rau serotonin syndrome. 
  • Tsis txhob muab tshuaj kho mob hnoos opioid rau cov neeg mob noj olanzapine. 
  • Xav txog kev sau tshuaj naloxone (Narcan) thaum muab tshuaj opioid.  

Xav paub ntau ntxiv