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Physician-administered drugs updates for providers

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Please review the following information on physician-administered drugs (PADs) changes and Alliance preferred PADs. Note: these updates are for Medi-Cal and IHSS only.

For more information on physician-administered drugs, including criteria and policies, please visit our website:

PADs changes effective June 1, 2026

The Alliance has made changes to physician-administered drug benefits. You can find prior authorization (PA) criteria on our website.

The changes are as follows:

HCPCS Code Drug Change Preferred Drug
J0013 Esketamine (Spravato) New PA criteria
J0585 OnabotulinumtoxinA (Botox) Modified PA criteria for diagnosis of chronic migraine Two or more of the following classes of preventive medications:

  • Anticonvulsants (topiramate, divalproex sodium, valproate sodium).
  • Beta-blockers (metoprolol, propranolol, timolol, atenolol, nadolol).
  • Tricyclic antidepressants (amitriptyline, nortriptyline).
  • SNRIs (venlafaxine, duloxetine).
  • CGRP targeting therapies such as erenumab (Aimovig),  fremanezumab (Ajovy), galcanezumab (Emgality), atogepant (Qulipta).
J0585 OnabotulinumtoxinA (Botox) New PA criteria for diagnosis of gastroparesis Metoclopramide, erythromycin and an antiemetic (such as ondansetron or promethazine)

The Alliance has updated the following pharmacy policies:

To request a copy, please call the Alliance Pharmacy Department at 831-430-5507.

Alliance preferred physician-administered drugs

This table is designed to support clinical decision making by highlighting Alliance preferred physician-administered drugs. Please consider these preferred options when appropriate, while continuing to use clinical judgment to determine the best therapy for each individual patient. Note: preferred medications may still require a prior authorization.

Therapeutic Class Alliance Preferred Medication (HCPCS) Non-Preferred Medication (HCPCS)
Granulocyte colony-stimulating factor (G-CSF) Filgrastim biosimilars:

  • Q5110 – Nivestym
  • Q5101 – Zarxio
  • J1447 – Granix
  • Q5125- Releuko
J1442- Neupogen (filgrastim)
Long-acting G-CSF J2506 – Neulasta (pegfilgrastim) Pegfilgrastim biosmilars:

  • Q5108 – Fulphila
  • Q5111 – Udenyca
  • Q5120 – Ziextenzo
  • Q5127 – Stimufend
  • Q5130 – Fylnetra
  • Q5122 – Nyvepria
Anti-CD20 monoclonal antibodies Rituximab biosimilars:

  • Q5115 – Truxima
  • Q5119 – Ruxience
  • Q5123 – Riabni
J9312 – Rituxan (rituximab)
Chemotherapy- bevacizumab Bevacizumab biosimilars:

  • Q5118 – Zirabev
  • Q5107 – Mvasi
  • Q5126 – Alymsys
  • Q5129 – Vegzelma
  • Q5160 – Jobevne
J9035 – Avastin
Anti-VEGF (ophthalmology) Avastin (J9035) trial first then Lucentis (J2778)
  • J0178 – aflibercept (Eylea)
  • Q5147 – aflibercept-avyh (Pavblu)
  • Q5149 – aflibercept-abzv (Enzeevu)
  • Q5150 – aflibercept-mrbb (Ahzantive)
  • Q5153 – aflibercept-yszy (Opuviz)
  • Q5155 – aflibercept-jbvf (Yesafili)
  • J0177 – aflibercept HD (Eylea HD)
  • Q5128 – ranibizumab-eqrn (Cimerli)
  • Q5124 – ranibizumab-nuna (Byooviz)
  • J2779 – ranibizumab implant (Susvimo)
  • J0179 – brolucizumab-dbll (Beovu)
  • J2777 – faricimab-svoa (Vabysmo)
Osteoporosis J3489 – Zoledronic acid
  • J0897 – denosumab (Prolia)
  • Q5157 – denosumab-bmwo (Stoboclo)
  • Q5158 – denosumab-bnht (Conexxence)
  • Q5136 – denosumab-bbdz (Jubbonti)
  • Q5161 – denosumab-kygg (Bosava)
  • Q5162 – denosumab-nxxp (Bildyos)
  • J3111 – romosozumab-aqqg (Evenity)
Injectable iron
  • J2916 – sodium ferric gluconate (Ferrlecit)
  • J1750 – iron dextran
  • J1756 – iron sucrose (Venofer)
  • J1439 – ferric carboxymaltose (Injectafer)
  • Q0138 – ferumoxytol (Feraheme)
  • J1437 – ferric derisomaltose (Monoferric)