Cov neeg uas muaj hom 2 mob ntshav qab zib mellitus muaj qhov ntau dua ntawm lipid abnormality, ua rau muaj kev pheej hmoo siab ntawm atherosclerotic cardiovascular disease (ASCVD). Statin tuaj yeem siv rau hauv cov neeg mob ntshav qab zib rau thawj thiab theem nrab tiv thaiv ASCVD cov xwm txheej.
Kev tshuaj xyuas kev siv tshuaj tsis ntev los no (DUR) tau pom tias ntau tshaj li ib feem peb ntawm peb cov tswvcuab uas muaj ntshav qab zib muaj hnub nyoog 40 thiab 75 xyoo tam sim no tsis noj statins. Thov tshuaj xyuas cov lus qhia hauv qab no thiab txiav txim siab seb txoj kev kho statin puas tsim nyog rau koj cov neeg mob.
Pib txoj kev kho statin
Lub koom haum American Diabetes Association (ADA) cov qauv kev saib xyuas rau cov ntshav qab zib tau pom zoo tias kev kho statin yuav tsum tau pib rau cov tib neeg uas muaj ntshav qab zib thiab lwm yam kev pheej hmoo ntawm cov hlab plawv tom qab kev ntsuas ceev (https://diabetesjournals.org/care/article/46/4/898/148368/Erratum-10-Cardiovascular-disease-and-risk).
- Rau cov neeg mob hnub nyoog 40 xyoo thiab laus dua uas muaj ntshav qab zib: Siv cov tshuaj kho mob statin txo qis.
- Rau cov neeg mob hnub nyoog 40 txog 75 xyoo uas muaj ntshav qab zib thiab muaj kev pheej hmoo siab dua (nrog rau cov neeg uas muaj ib lossis ntau dua ASCVD cov xwm txheej): Siv kev siv tshuaj statin siab kom txo qis LDL cov roj cholesterol los ntawm ≥50% ntawm lub hauv paus thiab tsom rau lub hom phiaj ntawm LDL roj cholesterol <70 mg / dL.
- Rau cov neeg mob ntshav qab zib uas twb muaj qhov tshwm sim ASCVD: Kev siv cov tshuaj statin siab tau pom zoo kom lub hom phiaj txo qis LDL roj cholesterol ntawm ≥50% los ntawm lub hauv paus thiab lub hom phiaj ntawm LDL roj cholesterol <55 mg / dL.
Tswj cov tsos mob uas cuam tshuam nrog statin
Lub koom haum American Heart Association 2018 thiab American College of Cardiology Guidelines on the Management of Blood Cholesterol pom zoo ib txoj hauv kev rau cov neeg mob uas muaj cov tsos mob ntawm statin, nrog rau tus kws kho mob rov ntsuam xyuas, sib tham thiab txhawb kev rov ua dua tshiab raws li thawj txoj hauv kev tshwj tsis yog cov kev mob tshwm sim hnyav (https://doi.org/10.1161/CIR.0000000000000625).
Qee qhov kev xaiv los txo cov leeg mob statin muaj xws li:
- Kev txo koob tshuaj statin (txo koob tshuaj thiab / lossis 3 zaug ib lub lim tiam piv rau kev noj txhua hnub).
- Hloov mus rau lwm qhov statin lossis hydrophilic statin (piv txwv li, pravastatin, rosuvastatin).
- Kev sib xyaw ua ke ntawm cov tshuaj statin nrog ezetimibe.
